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. Author manuscript; available in PMC: 2011 May 9.
Published in final edited form as: Mater Res Soc Symp Proc. 2009 Jan 1;1209:1209-YY03-01. doi: 10.1557/PROC-1209-YY03-01

Figure 1. T cell activation.

Figure 1

(A) Activation of T cells in vivo is mediated in large part by contact-mediated communication with Antigen Presenting Cells (APCs). (B) For therapeutic ex vivo expansion, activation is commonly carried out by replacing the APC with either engineered cells or beads that engage the same receptors involved in T cell/APC interaction.