. Author manuscript; available in PMC: 2011 Jul 1.

Published in final edited form as: Medicine (Baltimore). 2010 Jul;89(4):245–250. doi: 10.1097/MD.0b013e3181e9442f

TABLE 1.

Echocardiographic Findings in 44 Patients With Lipodystrophy Evaluated at the NIH

Mutation	No. of Patients	Age (yr)	LV Mass (g/m²)	LAV/BSA (mL/m²)	LV EF (%)	Cardiac Finding

AGPAT2	19	23±12	104±20	26±6	66±13	10 Patients with increased LV mass
						4 Patients with LV dysfunction
						1 Patient with PDA

Seipin	10	17±7	126±16	31±6	65±7	8 Patients with increased LV mass

LMNA	1	9	110	29	35	Moderate LV dysfunction and dilation, no increased LV mass

Unknown	1	17	71	16	68	Concentric remodeling

AGL	13	28±20	103±20	32±9	68±9	6 Patients with increased LV mass
						1 Patient with mild LV dysfunction

Abbreviations: AGL = acquired generalized lipodystrophy, LAV/BSA = left atrial volume indexed to body surface area, PDA = patent ductus arteriosus.