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. 2011 Mar 19;20(11):2251–2262. doi: 10.1093/hmg/ddr115

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© The Author 2011. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Retinal functional and morphological protection following AAV delivery in light-damaged albino Lewis rats. (A) ERG maximum B-wave amplitudes. The maximum B-wave amplitude from age-matched wild-type Lewis rats is 1291.3 ± 92 µV (n= 8). (B) The number of rows of PR nuclei in the ONL. The number of rows in age-matched wild-type Lewis rats is 11 ± 1.5 (n= 8). (A and B) Values are means ± SE. The number (n) of eyes in each group is depicted under the corresponding bar. CTRL, uninjected rats. Statistical significance has been calculated by ANOVA. *P ≤ 0.05. **P ≤ 0.001. In addition to those depicted in (A) and (B), significant differences (P < 0.05) were found between the following groups of rats: CTRL versus SR EPO; CTRL versus SR S100E; IM EPO versus SR EGFP; IM S100E versus SR EGFP; IM EPO versus SR S100E; IM EPO versus SR NP1–NP2.