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. 2011 Mar 19;20(11):2251–2262. doi: 10.1093/hmg/ddr115

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© The Author 2011. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Retinal morphological protection following AAV delivery in rds and Aipl1⁻^/⁻ mice. The number of rows of PR nuclei in the ONL of rds (A) and Aipl1^−/− (B) mice. Values are means ± SD. The number (n) of eyes (A and B) in each group is depicted under the corresponding bar. Statistical significance has been calculated by ANOVA. * and ∼ correspond to P ≤ 0.05; **P ≤ 0.001. ∼ refers to the comparison of the systemic versus the SR delivery of either EPO or S100E (A). In addition to those depicted in the figure, significant differences (P < 0.05) were found between the following groups of rds mice: CTRL versus SR EPO; CTRL versus SR S100E; CTRL versus SR NP1–NP2; IM EPO versus SR EGFP; IM S100E versus SR EGFP (A).