Figure 7.

Paired t test illustrating differences in brain activation between the main effects of pain and meditation across MRI sessions. Top, Noxious stimulation activated significantly greater SI corresponding to the stimulation site, bilateral SII, and bilateral insula before training when compared with after training. After training, noxious stimulation activated greater medial PFC, frontal pole, thalamus, and ACC when compared with before training. Bottom, There was greater superior temporal gyrus activation during the ATB condition before training compared with meditation after training. However, there was greater OFC, ACC, and right anterior insula meditation-related activation after training when compared with ATB before training. Slice locations correspond to standard stereotaxic space.