TABLE 2.
Comparison of gene expression and glycosphingolipid differences for nine cancer datasets
| Cancer Type | Gene Expression Ref. | Metabolite Ref. | G(i)M(i) | G(d)M(d) | G(i)M(d) | G(d)M(i) |
|---|---|---|---|---|---|---|
| MDA-MB231 / MCF7 | (36) | Current analysis and (48) | 4 | 8 | 4 | 2 |
| IDC / normal ductal | (43) | (14, 15, 49, 50) | 5 | 1 | ||
| Gliosarcoma | (76) | (77) | 2 | 1 | 1 | |
| GBM / white matter | (76) | (78) | 1 | 3 | 2 | 2 |
| Serious ovarian | (79) | (13, 80) | 2 | 1 | ||
| Mucinous ovarian | (79) | (13, 80) | 4 | 1 | ||
| SSEA3 / globo-H | (36) | (81) | 3 | 7 | 5 | |
| Melanoma cells | (16) | (16) | 6 | 9 | 5 | |
| Melanoma | (82) | (83) | 3 | |||
| Total | 30 | 28 | 18 | 6 |
The table compares the agreement G(i)M(i) and G(d)M(d), and disagreement G(i)M(d) and G(i)M(d), between gene expression and sphingolipid differences for nine cancer datasets. G, gene expression difference; M, metabolite difference; (i), higher ratio; and (d), lower ratio. The total for each category were used to determine the statistical significance as indicated in Fig. 8.