TABLE 2.

Precursor pool labeling and relative amounts of isotopomers formed for TG 54:3 and 54:4

Oral Formulation		1h	2h	3h	4h
Olive oil
TG 54:3	p (%)	41 ± 2	39 ± 2	34 ± 1	38 ± 3
	M0	3.10 ± 0.78	2.88 ± 0.48	3.62 ± 0.94	2.31 ± 0.66
	M1	0.38 ± 0.10	0.34 ± 0.05	0.40 ± 0.10	0.23 ± 0.07
	M2	0.13 ± 0.03	0.11 ± 0.01	0.11 ± 0.03	0.07 ± 0.02
	M3	0.02 ± 0.01	0.01 ± 0.00	0.01 ± 0.00	0.01 ± 0.00
TG 54:4	p (%)	29 ± 2	24 ± 1	21 ± 1	21 ± 1
	M0	3.29 ± 0.63	2.87 ± 0.39	3.10 ± 0.50	2.09 ± 0.42
	M1	0.17 ± 0.04	0.15 ± 0.02	0.19 ± 0.04	0.11 ± 0.03
	M2	0.03 ± 0.01	0.02 ± 0.00	0.02 ± 0.01	0.01 ± 0.00
Heavy cream
TG 54:3	p (%)	36 ± 2	32 ± 2	38 ± 5	37 ± 3
	M0	3.11 ± 0.27	2.52 ± 0.32	1.37 ± 0.19	1.57 ± 0.24
	M1	0.70 ± 0.08	0.55 ± 0.13	0.17 ± 0.03	0.16 ± 0.04
	M2	0.19 ± 0.02	0.13 ± 0.04	0.05 ± 0.01	0.04 ± 0.01
	M3	0.19 ± 0.04	0.07 ± 0.01	0.02 ± 0.01	0.01 ± 0.01
TG 54:4	p (%)	42 ± 2	38 ± 3	30 ± 1	29 ± 3
	M0	4.40 ± 0.38	3.85 ± 0.42	2.50 ± 0.32	2.87 ± 0.39
	M1	0.40 ± 0.09	0.41 ± 0.13	0.17 ± 0.04	0.16 ± 0.05
	M2	0.15 ± 0.04	0.14 ± 0.06	0.04 ± 0.01	0.04 ± 0.02
0.25% TPGS
TG 54:3	p (%)	94 ± 1	85 ± 2	79 ± 2	74 ± 3
	M0	0.40 ± 0.02	0.31 ± 0.02	0.33 ± 0.02	0.30 ± 0.04
	M1	0.10 ± 0.01	0.11 ± 0.01	0.08 ± 0.01	0.04 ± 0.01
	M2	0.85 ± 0.07	0.39 ± 0.10	0.17 ± 0.04	0.06 ± 0.01
	M3	21.06 ± 2.57	2.02 ± 0.62	0.44 ± 0.12	0.10 ± 0.03
TG 54:4	p (%)	95 ± 1	83 ± 3	75 ± 3	62 ± 4
	M0	2.31 ± 0.12	1.62 ± 0.09	1.76 ± 0.12	1.60 ± 0.21
	M1	0.29 ± 0.02	0.46 ± 0.02	0.34 ± 0.04	0.17 ± 0.03
	M2	2.49 ± 0.15	1.38 ± 0.36	0.59 ± 0.14	0.15 ± 0.03

Summary of precursor pool labeling (p, %) and relative amounts of isotopomers (M₀, M₁, M₂, M₃) formed for TG 54:3 and 54:4 at different time points following po administration of ¹³C₁₈-oleic acid (480 mg/kg) in formulations containing different amounts of lipid. Data are presented as means ± SEM; values listed for the isotopomers are in units of corrected response (see Materials and Methods for details).