TABLE 3.
Precursor pool labeling (p) and relative amounts of isotopomers formed for TG 52:2 and 54:3
| Mean ± SEM amounts of isotopomer formed | |||||
|---|---|---|---|---|---|
| Dose | p (%) | M0 | M1 | M2 | M3 |
| 10 mg/kg | |||||
| TG 52:2 | 22 ± 2 | 63.04 ± 7.03 | 0.56 ± 0.11 | 0.08 ± 0.02 | — |
| TG 54:3 | 38 ± 1 | 74.95 ± 10.97 | 0.23 ± 0.05 | 0.07 ± 0.01 | 0.02 ± 0.01 |
| 50 mg/kg | |||||
| TG 52:2 | 53 ± 2 | 66.44 ± 5.42 | 2.06 ± 0.37 | 1.11 ± 0.15 | — |
| TG 54:3 | 80 ± 1 | 91.50 ± 17.48 | 1.02 ± 0.08 | 2.14 ± 0.22 | 2.72 ± 0.41 |
| 150 mg/kg | |||||
| TG 52:2 | 73 ± 1 | 58.11 ± 6.94 | 2.10 ± 0.38 | 2.80 ± 0.53 | — |
| TG 54:3 | 87 ± 1 | 84.41 ± 19.02 | 1.25 ± 0.21 | 4.11 ± 0.83 | 11.64 ± 2.57 |
Summary of precursor pool labeling (p, %) and relative amounts of isotopomers (M0, M1, M2, M3) formed for TG 52:2 and 54:3 measured 30 min after iv administration of the [13C18] oleic acid label to 4 h-fasted mice. Data are presented as means ± SEM; values listed for the isotopomers are in units of corrected response (see Materials and Methods for details).