TABLE 2.
The minimum value, maximum value, median, and mean ± SD for plasma D-4F levels are shown for the mice described in Fig. 4
D-4F Dose μg/mouse/day | Route of Administration | Minimum Value | Maximum Value | Median | Mean ± SD |
---|---|---|---|---|---|
3 | Oral | BLLOQ | 65 ng/ml | BLLOQ | 17 ± 4 ng/ml |
3 | SQ | BLLOQ | 660 ng/ml | 56 ng/ml | 150 ± 196 ng/ml |
9 | Oral | BLLOQ | BLLOQ | BLLOQ | BLLOQ |
9 | SQ | 317 ng/ml | 625 ng/ml | 410 ng/ml | 442 ± 96 ng/ml |
90 | Oral | BLLOQ | 7 ng/ml | 1 ng/ml | 2 ± 2 ng/ml |
90 | SQ | 2.3 μg/ml | 5.7 μg/ml | 4.0 μg/ml | 3.8 ± 1 μg/ml |
900 | Oral | 2 ng/ml | 94 ng/ml | 27 ng/ml | 35 ± 28 ng/ml |
900 | SQ | 23 μg/ml | 61 μg/ml | 39 μg/ml | 39 ± 11 μg/ml |
BLLOQ, below lower limit of quantification.