Table 4.
Genotype frequencies for the mannose binding lectin-2 (MBL2) codon 52, 54, 57, and MBLXY polymorphisms among patients and controls and among survivors and nonsurvivors in acute respiratory distress syndrome (ARDS)
| Percentage of Patients (No.) |
||||||
|---|---|---|---|---|---|---|
| Polymorphism | Controls (n = 442) |
Cases (n = 212) |
p Value | Survivors in ARDS (n = 144) |
Nonsurvivors in ARDS (n = 98) |
p Value |
| Codon 52 | ||||||
| 52AA | 82 (345) | 86 (170) | 90 (97) | 82 (73) | ||
| 52AD | 17 (72) | 14 (27) | .4 | 10 (11) | 18 (16) | .1 |
| 52DD | 0.5 (2) | 0 (0) | 0 | 0 | ||
| Codon 54 | ||||||
| 54AA | 72 (319) | 71 (151) | 68 (78) | 74 (73) | ||
| 54AB | 27 (120) | 25 (54) | <.05 | 31 (35) | 19 (19) | .03 |
| 54BB | 0.7 (3) | 3.3 (7) | 1 (1) | 6 (6) | ||
| Codon 57 | ||||||
| 57AA | 97 (418) | 98 (205) | 98 (111) | 97 (94) | ||
| 57AC | 3 (12) | 2 (5) | >.9 | 2 (2) | 3 (3) | .5 |
| 57CC | 0.2 (1) | 0 (0) | 0 | 0 | ||
| MBLXY | ||||||
| YY | 71 (306) | 65 (136) | 67 (75) | 64 (61) | ||
| XY | 26 (111) | 29 (60) | .2 | 26 (29) | 32 (31) | .5 |
| XX | 3 (15) | 6 (12) | 7 (8) | 4 (4) | ||
Fisher’s exact test p values are reported.