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. Author manuscript; available in PMC: 2011 May 9.
Published in final edited form as: Structure. 2010 Feb 10;18(2):155–166. doi: 10.1016/j.str.2009.12.012

Table 2.

Effect of RIα mutations on D-AKAP2 bindinga

RIα construct KD (nM)
Wild type 48
C16A 126 (3-fold)b
C37A 745 (16-fold)
Y19A 1329 (27-fold)
H23A 198 (4-fold)
a

KD=EC50 calculated from curves fit to 1:1 binding model.

b

Values in parentheses denote the relative decrease in binding.