. 2011 May 2;7:241–249. doi: 10.2147/NDT.S10997

Table 3.

Structure MRI and magnetic resonance spectroscopy imaging studies of posttraumatic stress disorder (PTSD) in China

Author	Subjects	Method	Result
Chen et al²¹	12P (26–52, 34 ± 5) 8F 4M 12 NP (27–50, 33 ± 5) 8F 4M	DSM-IV SCID MRI VBM	Gray matter density in the left hippocampus, left anterior cingulate cortex, and bilateral insulars↓
Xiong et al²³	30P (18–50, 28.33 ± 10.79) 20F 10M 30C (18–50, 35.4) 18F 12M	CCMD-3 MRI ROI	Volume of the bilateral hippocampus↓
Yang et al²²	17P (13–62, 37.2) 10F 7M 17C (14–62, 38.5)	DSM-IV MRI MRS	Volume of the left hippocampus↓
Yang et al²²	17P (13–62, 37.2) 10F 7M 17C (14–62, 38.5)	DSM-IV MRI MRS	NAA and Cr level in the bilateral hippocampus↓
Chen et al²⁴	12P (26–47, 34) 8F 4M 12C 6NP (26–45) 4F 2M 6HC (28–47) 4F 2M	DSM-IV SCID MRS	NAA/Cr ratio in the left hippocampus↓
Xia et al²⁵	19P (31.2 ± 7.4) 13F 6M 19C (34.4 ± 8.1) 14F 5M	CCMD-3 MRS	NAA and NAA/Cr in the bilateral hippocampus↓

Abbreviations: P, patients; F, female; M, male; NP, victims of the same fire without PTSD; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, 4th edition; SCID, Structured Clinical Interview for DSM-IV; MRI, magnetic resonance imaging; VBM, voxel-based morphometry; C, controls; CCMD-3, Chinese Classification and Diagnostic Criteria of Mental Disorders 3rd version; ROI, region of interesting; MRS, magnetic resonance spectroscopy; NAA, N-acetylaspartic acid; Cr, creatine.