Skip to main content
. 2003 Dec;41(12):5770–5773. doi: 10.1128/JCM.41.12.5770-5773.2003

TABLE 2.

Amino acid variations in HA1 sequences of influenza B viruses

Group or strain Amino acid residue at positione:
29 34 40 48 56 58 75 76 78 87 88 116 126 127 148 159 162 164 168 175 176 179 180 182 183 184 197 199 220 225 233
Group 1a
    B/Victoria/504/00b A T H K T L I T S V K K N A S A R D T V E H I T K E D T I V E
    WV5 V Y R D T R N D K N Y V K E G N V D
    WV27 I R I N D
    WV29 R G I N D
    WV34 M Y
    WV50 P R D N N D
    WV56 A R I N D
    WV57 F R D N N D
    WV78 R D K N D
    WV114 F P R D N N D
    WV166 R T I N D
    WV194 F R D N N D
    WV45,51 F R D N N D
    WV22,33,126, 183,4,41,42 R I N D
    WV106,107,133, 26,43,65,66,67, 69,70,73 F R D N D
Group 2c
    B/Hong Kong/330/01b V T H K K L N I S V R R N A V A K D T I E Y I T E G S T V V N
    WV122 T N A
    WV124,135,158 N
Group 3d
    B/Hong Kong1351/02b V T H K K L N I S V R H N A V A K D T I E Y I T E G K T V V N
    WV36,109 N
    WV137,142,143,145, 146,150,153,161, 169,170,174,187 V N
a

n = 31 specimens. Amino acid substitution frequencies are 55% (position 58), 97% (position 88), 58% (position 126), 39% (position 175), 97% (position 197), and 97% (position 233).

b

Reference strain.

c

n = 4 specimens. Amino acid substitution frequency was 100% at position 197.

d

n = 14 specimens. Amino acid substitution frequencies are 86% (position 159) and 100% (position 197).

e

—, amino acid residue identical to that in the reference strain. Amin with high frequency variations (>35%) are shown in bold characters.