Table 1.
Generic name | Trade name | Half lifea (metabolite) | Pediatric FDA approval | Dosing | Generic form |
---|---|---|---|---|---|
Valsartan | Diovan | 6 hours | Yes | 80–160 mg | No |
Losartan | Cozaar | 2 (6–9) hours | Yes | 50 mg | Yes |
Irbesartanb | Avapro | 11–15 hours | No | 150–300 mg | No |
Telmisartan | Micardis | 24 hours | No | 40–80 mg | No |
Candesartan cilexetil | Atacand | 9 hours | Yes | 4–32 mg | No |
Eprosartan | Teveten | 5–9 hours | No | 400–800 mg | No |
Olmesartan | Benicar | 13 hours | Yes | 10–40 mg | No |
Notes:
From www.medscape.com;
Irbesartan in a study at a dose of up to 4.5 mg/kg/day once daily did not appear to lower blood pressure effectively in pediatric patients aged 6 to 16 years. Avapro has not been studied in pediatric patients less than 6 years old.