Skip to main content
. 2011 May 9;6(5):e19418. doi: 10.1371/journal.pone.0019418

Table 2. In-vitro antibacterial activities of inhibitors of PBPs from resistant species.

Bacterial Strain MIC (µg/mL)
1 2 6 9 10 12 Ampicillin
Escherichia coli ATCC 8739 >1024 >512 >512 >512 >512 >512 4
Proteus mirabilis ATCC 29936 >1024 >512 >512 >512 >512 >512 2
Citrobacter freundii ATCC 8090 >1024 >512 >512 >512 >512 >512 128
Pseudomonas aeruginosa ATCC 27853 >1024 >512 >512 >512 >512 >512 >1024
Klebsiella pneumoniae ATCC 13883 >1024 >512 >512 >512 >512 >512 256
Micrococcus luteus ATCC 9341 2 >512 32 16 256 256 0.5
Listeria innocua ATCC 33090 16 >512 64 16 256 >512 0.25
Listeria monocytogenes ATCC 14780 16 >512 64 16 32 >512 0.5
Bacillus subtilis ATCC 6633 2 >512 128 32 256 >512 0.5
Enterococcus faecalis ATCC 7937 16 >512 64 64 256 >512 2
Enterococcus faecalis ATCC 29212 32 >512 32 64 256 256 2
Enterococcus faecium ATCC 19434 64 >512 256 16 128 >512 64
Enterococcus hirae ATCC 8790 16 >512 32 16 128 256 64
Streptococcus pneumoniae ATCC 49619 1 >512 32 1 2 256 0.06
Streptococcus pneumoniae ATCC 33400 1 >512 64 1 2 256 0.03
Streptococcus pneumoniae D39 1 >512 16 1 2 256 0.06
Staphylococcus epidermidis ATCC 12228 32 >512 16 8 128 256 16
Staphylococcus aureus ATCC 25923 32 >512 16 32 128 512 0.25
Staphylococcus aureus ATCC 43300 (MRSA) 32 >512 128 32 256 512 1024
Staphylococcus aureus mp 1 (inducible MRSA) 32 >512 128 32 256 512 1024