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. 2011 May 9;6(5):e19481. doi: 10.1371/journal.pone.0019481

Figure 3. Modest levels of miR-499 expression results in mild hypertrophy.

Figure 3

(A) Gross appearance of hearts from miR-499 transgenic mice (line #17, TG-17) and littermate controls (WT) was similar. (B) Heart-to-body weight ratios in TG-17 and WT, n = 4–6 mice per group. (C) Fractional shortening of WT or TG-17 mice by echocardiography. (D) WGA staining of histological sections of hearts from TG-17 and WT mice; magnification 200×. (E) Quantification of cardiomyocyte size revealed an increase in TG-17 (RV and LV both *P<0.05).