Skip to main content
. 2011 Apr 13;31(15):5682–5692. doi: 10.1523/JNEUROSCI.5453-10.2011

Figure 4.

Figure 4.

Paired-pulse depression and facilitation measured with Cm changes from hair cells. Hair cells were depolarized from −90 to −30 mV. A, ICa and ΔCm evoked by a pair of 20 ms pulses with 20 ms interpulse interval shows paired-pulse facilitation (ΔCm2/ΔCm1 > 1). B, ICa and ΔCm evoked by a pair of 20 ms pulses with 200 ms interpulse interval. ΔCm2/ΔCm1 was close to 1. C, The averaged ratio of ΔCm (ΔCm2/ΔCm1) evoked by a pair of 20 ms voltage steps from −90 to −30 mV with interpulse interval of 20, 50, 100, and 200 ms. D, ICa and ΔCm evoked by a pair of 200 ms pulses with 500 ms interpulse interval. E, Recovery from depression elicited by a pair of 200 ms pulses. The averaged ΔCm2/ΔCm1 was measured with various interpulse intervals (20 ms, 50 ms, 100 ms, 200 ms, 500 ms, 1 s, 2 s, 5 s, 10 s, and 15 s; n = 4–17). Paired-pulse depression recovered with a two exponential time course with time constants of 83.8 ms (τ1) and 2.9 s (τ2). F, ΔCm evoked by a pair of voltage steps from −90 to −30 mV for various durations (20, 100, 200, and 500 ms) with 500 ms interpulse interval. The dashed line indicates that ΔCm2/ΔCm1 is 1.