Skip to main content
. Author manuscript; available in PMC: 2011 May 9.
Published in final edited form as: Am J Gastroenterol. 2009 Jul 7;104(9):2153–2160. doi: 10.1038/ajg.2009.300

Table 3.

Association of p16 and/or APC promoter hypermethylation with progression to high-grade dysplasia or cancer

Clinical Outcome of patients p16 p APC p Both genes p
Progressed from baseline pathology to high-grade dysplasia or cancer 100% 86% 100%
Did not progress from baseline pathology 33% 40% 24%
Odds Ratios (95% CI) 10.02 (1.18–inf) 0.034* 9.00 (1.01–80.52) 0.049* 14.97 (1.73–inf) 0.012*
*

denotes statistical significance at p<0.05