Table 5.
Mean (±SEM) repetitive motor movements (RMM), head-down sniffing counts, and behavioral intensity scores of drug-treated preweanling rats collapsed across time blocks 9–16 (Experiment 3)
Drug Infusion | RMM | Sniffing | Behavioral Intensity |
---|---|---|---|
Vehicle | 223.7 (±54) | 0.30 (±0.10) | 0.18 (±0.14) |
10 μg Quinpirole | 677.9 (±34)* | 6.99 (±0.61)* | 2.83 (±0.07)* |
1 μg SCH-23390 | 114.4 (±22)† | 0.09 (±0.03)† | 0.03 (±0.02)† |
5 μg SCH-23390 | 77.7 (±22)† | 0.84 (±0.74)† | 0.22 (±0.21)† |
1 μg SCH-23390/Quinpirole (10 μg) | 615.2 (±40)* | 4.92 (±1.10)* | 1.50 (±0.39) |
5 μg SCH-23390/Quinpirole (10 μg) | 670.5 (±67)* | 6.99 (±0.61)* | 1.38 (±0.19) |
Repetitive motor movement values represent mean total scores collapsed across the final 40-min testing phase, whereas head-down sniffing and behavioral intensity values represent mean scores per 5-min time block during the final 40-min testing phase.
Significantly different from the vehicle group.
Significantly different from the 10 μg quinpirole group.