Table 1.
Amounts of cytokines and chemokines in lungs of mice infected with F. tularensis strain SchuS4 in comparison with those infected with similar dose of F. novicida strain U112.
| Immune mediator | Amount in SchuS4 infected lungs | Amount in U112 infected lungsa |
|---|---|---|
| IFN-γ | 569 ± 54 pg | 712 ± 380 pg |
| IL-10 | 1059 ± 4 pg | 983 ± 67 pg |
| IL-18 | 30 ± 2.3 ng | 7 ± 0.3 ng |
| IL-6 | 5167 ± 168 pg | 2470 ± 617 pg |
| IL-1α | 6 ± 0.6 ng | 8 ± 1.8 ng |
| IL-1β | 17 ± 0.6 ng | 10 ± 0.9 ng |
| CCL2 | 24 ± 0.4 ng | 17 ± 5 ng |
| CCL4 | 3.3 ± 0.12 ng | 6.4 ± 1.7 ng |
| CCL9 | 8.5 ± 0.4 ng | 13.5 ± 1.6 ng |
| CXCL1 | 12 ± 0.8 ng | 5 ± 0.6 ng |
| CXCL10 | 35 ± 3.4 ng | 29 ± 7 ng |
| CXCL6 | 1.6 ± 0.06 ng | 19 ± 2.7 ng |
| TNF-α | 538 ± 35 pg | 862 ± 122 pg |
Reference [13]