Table 4.

Energy and Fluid Intake by Degree of Critical Illness (Step 2: Unadjusted and Adjusted Analyses)

Energy Intake*(kcal/kg/day)Fluid Intake* (cc/kg/day)	AGA Critically Ill			SGA Critically Ill
	Less (MV < 7d) (n=499)	More (MV d 1–7) (n=646)	p-value†	Less (MV < 7d) (n=145)	More (MV d 1–7) (n=76)	p-value†
Days 1–7
Parenteral Energy	46.1 (12.5)	41.1 (12.5)	<0.0001	44.4 (11.7)	39.4 (13.1)	0.0006
Non-protein	38.7 (10.8)	33.3 (10.7)	<0.0001	36.9 (10.0)	30.9 (10.5)	<0.0001
Protein	7.4 (2.5)	7.8 (3.2)	0.34	7.5 (2.9)	8.5 (3.6)	0.041
Enteral Energy**	3, 5.8 (8.1)	0, 1.6 (3.5)	<0.0001	3, 8.0 (12.4)	0, 1.7 (3.0)	0<.0001
Total Energy	52.0 (13.8)	42.7 (13.1)	<0.0001; <0.0001‡	52.4 (13.9)	41.1 (13.4)	<0.0001 ; <0.0001‡
Total Fluid Intake	123 (25)	130 (33)	0.001; 0.09‡	117 (23)	126 (34)	0.037; 0.26‡
Days 8–14
Parenteral Energy	62.5 (26.4)	69.5 (18.0)	0.0010	59.3 (30.6)	65.9 (15.9)	0.41
Non-protein	52.2 (22.3)	56.5 (15.5)	0.047	49.0 (25.6)	52.7 (13.6)	0.66
Protein	10.3 (5.0)	13.0 (4.6)	<0.0001	10.4 (6.1)	13.2 (4.9)	0.002
Enteral Energy**	24, 32.7 (29.5)	5, 12.1 (17.9)	<0.0001	31, 39.0 (35.0)	6, 12.9 (15.0)	<0.0001
Total Energy	95.2 (17.0)	81.6 (19.5)	<0.0001; <0.0001‡	98.3 (17.1)	78.7 (20.9)	<0.0001 ; <0.0001‡
Total Fluid Intake	151 (19)	151 (27)	0.89; 0.48‡	148 (20)	147 (28)	0.89; 0.66‡
Days 15–21
Parenteral Energy	41.3 (34.9)	58.5 (28.8)	<0.0001	36.4 (36.1)	60.5 (27.4)	<0.0001
Non-protein	34.9 (29.7)	48.3 (24.4)	<0.0001	30.5 (30.4)	49.6 (22.6)	<0.0001
Protein	6.4 (5.7)	10.2 (5.6)	<0.0001	5.9 (6.3)	10.8 (6.0)	<0.0001
Enteral Energy**	52, 58.2 (42.4)	16, 30.7 (35.7)	<.0001	70, 68.6 (44.5)	23, 31.8 (32.9)	<0.0001
Total Energy	99.5 (20.8)	89.2 (21.8)	<0.0001; <0.0001‡	105.0 (19.4)	92.2 (20.8)	<0.0001; <0.0001‡
Total Fluid Intake	139 (27)	142 (25)	0.068; 0.30‡	132 (27)	146 (15)	0.0005; 0.0028‡

^*Presented as mean (standard deviation), except where noted.

^**Presented as median, mean (standard deviation).

^†p-values from Wilcoxon test.

^‡p-value after adjusting for birth weight stratum in GLM procedure.