. Author manuscript; available in PMC: 2011 May 10.

Published in final edited form as: J Proteome Res. 2011 Mar 28;10(5):2359–2376. doi: 10.1021/pr101148r

Table 3a.

ROC analysis and Wilcoxin rank-sum test - Pancreatic cancer biomarker candidates.

Marker candidate	Cancer cases vs non-disease control						Cancer cases vs all controls (non-disease control and chronic pancreatitis)
Marker candidate	AUC	Sens at 100% Spec	Sens at 95% Spec	Spec at 100% Sens	Spec at 95% Sens	p value (Wilcoxin rank-sum test)	AUC	Sens at 100% Spec	Sens at 95% Spec	Spec at 100% Sens	Spec at 95% Sens	p value (Wilcoxin rank-sum test)
TIMP1	0.83	54%	54%	22%	22%	<0.0001	0.82	38%	54%	19%	21%	<0.0001
ICAM1	0.83	55%	65%	11%	15%	0.0001	0.80	40%	55%	7%	11%	0.0002
THBS1	0.68	0%	0%	0%	11%	0.1600	0.70	0%	13%	0%	16%	0.0385
CCL5	0.51	0%	0%	22%	22%	1.0000	0.61	0%	0%	6%	6%	0.3180
LBP	0.58	12%	29%	0%	0%	0.4280	0.51	12%	18%	3%	3%	0.9284
PPBP	0.52	0%	0%	42%	42%	0.8709	0.61	0%	0%	42%	42%	0.2600
CA19-9	0.58	0%	0%	5%	5%	0.4884	0.57	0%	8%	0%	0%	0.4750