Figure 5. Tumor growth delay in response to various treatment regimens.
Normalized mean tumor volume is shown for each treatment group. While a single dose of CA4P caused significant inhibition of tumor growth on day 3, the tumors rapidly caught up with the control tumors by day 7. Combined treatment provided little additional benefit on day3, but the tumors receiving combined therapy were all smaller than the Controls on day 7. The most significant tumor growth delay was seen in the tumors treated with CA4P followed by radiation plus oxygen 24 h later (CA4P + 24 h (IR + O2)).