Table 1. Relative tumor growth with respect to treatment.
Relative tumor volume (RTV) | |||
---|---|---|---|
Group | Day 3 | Day 7 | Day 14 |
Control | 2.33 ± 0.55 | 2.84 ± 0.81 | |
CA4P | 1.11 ± 0.14a | 3.33 ± 0.45 | |
Radiation (IR) | 1.28 ± 0.12a | 2.00 ± 0.23 | 2.83 ± 0.88 |
IR + O2 | 1.04 ± 0.14a | 1.80 ± 0.35a | 3.49 ± 0.87 |
CA4P + 24h IR | 1.01 ± 0.11a | 1.79 ± 0.29a | 2.89 ± 0.45 |
IR + 1h CA4P | 1.46 ± 0.22a | 2.10 ± 0.23 | 2.14 ± 0.35 |
(IR + O2) + 1h CA4P | 1.02 ± 0.11a | 1.20 ± 0.08a,b | 2.35 ± 0.42 |
CA4P + 24h (IR + O2) | 0.96 ± 0.05a,b | 0.60 ± 0.20a,b | 1.51 ± 0.25c |
p < 0.05 from control;
p < 0.05 from IR group;
p < 0.05 from any of the other treatment groups (Student's t-test).
The animals in Control and CA4P alone were sacrificed on Day 7. CA4P was administered as a single dose of 30 mg/kg. IR was delievered as a single dose 5 Gy.