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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Dev Biol. 2011 Apr 2;354(1):102–110. doi: 10.1016/j.ydbio.2011.03.025

Fig. 2. Mesoderm in spt morphants displays abnormal morphology.

Fig. 2

(A) Cells in the hypoblast of spt morphant embryos blebbed extensively and failed to adopt the proper mesenchymal morphology. (B) Cell protrusions were quantified in wild-type embryos during and after involution, in the hypoblast of spt morphants and in spt morphants expressing spt under the control of a heat shock-sensitive promoter. Mesodermal cells in spt morphants blebbed far more than in wild-type hypoblast, whereas restoring Spadetail significantly reduced this blebbing. Error bars indicate one standard deviation. At least 22 cells were quantified per condition. p<0.05 for data marked with an asterisk.