Decreased sodium pump expression reduces Orai1 gene expression during embryonic development. A, When β3 levels are knocked down, transcript levels of Orai1 are significantly reduced between stages 15 and 28 (*p < 0.05, **p < 0.01). Decreased β3 levels do not cause significant changes in Notch1 (B), Olig2 (C), and Olig4 (D) transcripts at the stages examined. All values are means ± SEM for n ≥ 3 independent experiments.