. 2011 Feb 8;5(2):681–687. doi: 10.1007/s12072-010-9232-0

Table 3.

Hepatitis C-related liver cirrhosis estimated relative risk associated with the number of putative high-risk genotypes of IL-18, IFN-γ, and IL-10 genes

	Liver cirrhosis (−)	Liver cirrhosis (+)	OR (95% CI)^b	p^b	OR (95% CI)^c	p^c
	n = 31 (f)	n = 46 (f)	OR (95% CI)^b	p^b	OR (95% CI)^c	p^c
Age	50.7 ± 7.6	60.5 ± 9.2	–	<0.0001	–	0.001
Sex
Male	5 (0.16)	16 (0.35)	2.77 (0.80–10.12)	0.07	1.54 (0.38–6.25)	0.539
Female	26 (0.84)	30 (0.65)	1
No. of high risk genotypes^a
0–2	18 (0.58)	10 (0.22)	1		1
3–4	13 (0.42)	36 (0.78)	4.98 (1.65–15.46)	0.002	5.19 (1.49–18.05)	0.009

^aIL-18 −607C/*, IL-18 −137G/*, IFN-γT/*, IL-10AA were considered as putative high-risk genotypes

^bCrude odds ratios

^cOdds ratios adjusting by sex and age