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. 2011 Jan 10;589(Pt 8):1911–1925. doi: 10.1113/jphysiol.2010.201475

Figure 3. Hyperpolarising effect of dopamine on the Im cells.

Figure 3

A, response of Im cell to superimposed depolarising current pulses (60 pA, 200 ms) during control, dopamine bath application (DA, 30 μm) and washout. B, average (±s.e.m.) effect of dopamine on the resting membrane potential (RMP, n = 20), number of action potentials (APs; n = 20) and input resistance (Rin; n = 8). Comparison between control and DA bath application (***P < 0.001; **P < 0.01). C, average (±s.e.m.) effect of dopamine on the resting membrane potential (RMP) in the presence of the D1R antagonist SCH 23390 hydrochloride (5 μm, P > 0.1, n = 4) or the D2R antagonist sulpiride (5 μm, **P < 0. 01, n = 4).