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. 2011 Apr 19;2011:252361. doi: 10.1155/2011/252361

Figure 2.

Figure 2

Capture of T24 and SKOV cells spiked into blood. A: the percentage capture of T24 cells using anti-EpCAM antibody. B: T24 capture % using anti-EpCAM and TROP-2 antibodies. C: SKOV capture % using anti-EpCAM antibody; D: SKOV capture % using anti-EpCAM and TROP-2 antibodies. By FACS T24 cells were shown to contain 4,000 and 60,000 EpCAM and TROP-2 antigens, respectively; SKOV cells were shown to contain 66.000 and 12,000 EpCAM and TROP-2 antigens, respectively. Antibody capture is less efficient with low-antigen expression on the cells, but increases in an additive manner when antibodies are used in combination.