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. Author manuscript; available in PMC: 2011 May 10.
Published in final edited form as: JAMA. 2009 Jul 1;302(1):49–57. doi: 10.1001/jama.2009.943

Table 5.

Reclassification of 10-year predicted risk

Cardiovascular Events

Model with conventional risk factors alone Model with conventional risk factors and biomarkers

<6% 6% to <20% ≥20% Total

<6% Total N 3,092 123 0 3,215
N with events 65 7 0 72
% with events 2.1% 5.7% 0% 2.2%

6% to <20% Total N 143 920 35 1,098
N with events 10 109 6 125
% with events 7.0% 11.8% 17.1% 11.4%

≥20% Total N 0 34 136 170
N with events 0 4 37 41
% with events 0% 11.8% 27.2% 24.1%

Total Total N 3,235 1,077 171
N with events 75 120 43
% with events 2.3% 11.1% 25.1%

Coronary Events

Model with conventional risk factors alone Model with conventional risk factors and biomarkers

<6% 6% to <20% ≥20% Total

<6% Total N 3,891 85 0 3,976
N with events 72 9 0 81
% with events 1.8% 10.6% 0% 2.0%

6% to <20% Total N 110 443 22 575
N with events 3 45 2 50
% with events 2.7% 10.2% 9.1% 8.7%

≥20% Total N 0 14 35 49
N with events 0 2 11 13
% with events 0 14.3% 31.4% 26.5%

Total Total N 4,001 542 57
N with events 75 56 13
% with events 1.9% 10.3% 22.3%

The number of events differ from the main analyses, because the table is restricted to events occuring during the first 10 years of follow up.