Table 1.

Clinical characteristics of patients with idiopathic dilated cardiomyopathy compared with control group

	Control subjects (n = 26)	Patients with idiopathic dilated cardiomyopathy (n = 35)
		Total	Normal IL-10 response (n = 22)	Heightened IL-10 response (n =13)
Age (years)	46 ±13	53 ± 11 *	51 ±13	57 ± 7
Male (%)	46	60	63	54
Hypertension (%)	31	37	45	23
Diabetes Mellitus (%)	0	22 *	27	15
Dyslipidemia (%)	31	46	41	54
Atrial fibrillation (%)	0	34 *	27	46
History of smoking (%)	8	11	13	8
Systolic blood pressure (mm Hg)	115 ± 11	111 ± 19	117 ± 18	101 ± 16 †
BMI	27 ± 5	37 ± 33 *	41 ± 42	29 ± 3
NYHA Class (I-II/III, %)	N/A	74/26	72/28	77/23
CRT/ICD (%)	N/A	54	55	50
Serum Creatinine (mg/dL)	0.8 ± 0.2	1.0 ± 0.26*	0.9 ± 0.2	1.0 ± 0.3
hsCRP (mg/L)	1.8 ± 1.8	6.0 ± 8.9*	8.3 ± 10.5	2.0 ± 2.0 †
ACEI/ARB (%)	19	86*	81	92
B-blocker (%)	11	89*	91	92
Aldosterone inhibitor (%)	4	37*	32	46
Statin (%)	15	60*	64	54
Diuretic (%)	4	60*	52	80

Abbreviations: IL-10 – interleukin 10, BMI – body mass index, NYHA –New York Heart Association, CRT – Cardiac resynchronization therapy, ICD – Implantable cardiac defibrillator, hsCRP – high sensitivity C reactive protein, ACEI – angiotensin converting enzyme inhibitor, ARB – angiotensin receptor blocker, B-blocker – beta blocker.

^*p value < 0.05 when comparing control subjects and overall patient group.

^†p value < 0.05 when comparing normal and heightened response groups in patients with iDCM.