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LanthaScreen™ profile of 3 using the invitrogen lipid kinase panela
| Kinase | IC50(nM) | Kinase | IC50(nM) |
|---|---|---|---|
| PI4K α | >10000 | P110 α/p85α | 4.68 |
| PI4K β | 18.3 | P110δ/P85α | 17.5 |
| PI3K-C2 α | 28.1 | P110γ | 5.67 |
| PI3K-C2β | 24.5 | DNA-PK | 0.5 |
| hVPS34 | 8.58 | mTOR | 2.81 |
Kinase targets were tested with biochemical enzymatic kinase assays using the SelectScreen® Kinase Profiling Service (Life Technologies Corporation, Madison, WI)
