Table 5.
Summary of pharmacokinetic parameters of resveratrol sulfate and pterostilbene sulfate following a daily oral dosing for 1 and 14 days
| Chemical | Dose (mg/kg) | Number of doses | Tmax (h) | Cmax (ng/mL) | AUC0–inf (ng*h/mL) | T1/2 (h) |
|---|---|---|---|---|---|---|
| Resveratrol | 50 | 1 | 4 | 2,020 | 12,600 | 3.2 |
| Pterostilbene | 56 | 1 | 4 | 1,970,000 | 1,280,000 | 1.3 |
| Resveratrol | 50 | 14 | .25 | 2,770 | 12,200 | .93 |
| Pterostilbene | 56 | 14 | 4 | 2,060,000 | 1,110,000 | 1.5 |
| Resveratrol | 150 | 1 | 1 | 8,710 | 46,000 | 3.2 |
| Pterostilbene | 168 | 1 | 8 | 2,630,000 | 2,450,000 | 1.6 |
| Resveratrol | 150 | 14 | 2 | 10,500 | 56,400 | 1.6 |
| Pterostilbene | 168 | 14 | 6 | 2,050,000 | 2,130,000 | 1.6 |