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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Drug Alcohol Depend. 2011 Apr 3;115(1-2):137–144. doi: 10.1016/j.drugalcdep.2011.01.009

Figure 2.

Figure 2

This figure presents the regions exhibiting unique variance associated with the cocaine videos in the hierarchical regression analysis for chronic cocaine abuser (CCA; Panel A) and healthy control (HC; Panel B) groups. Cocaine videos elicited activation (warm colors; red: .001 < p ≤ .005, yellow: p ≤ .001) within the frontal craving network areas for CCA, including bilateral orbital frontal cortex (OFC) and dorsolateral prefrontal cortex (DLPFC), with minimal deactivation of the default-mode network. In contrast, deactivation (cool colors; blue: .001 < p ≤ .005, cyan: p ≤ .001) of the default-mode network was prominent for HC and included the anterior cingulate gyrus (ACC) and posterior cingulate gyrus (PCC). Axial (z) and sagittal (x) slice locations are provided according to the Talairach atlas (L= left and R = right).