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. 2011 May 28;5(Suppl 2):S3. doi: 10.1186/1753-6561-5-S2-S3

Table 1.

comparison for unsupervised methods: Silhouette coefficients and number of genes for each cluster and unsupervised clustering method (no labels). Laplacian Eigenmaps+k-means leads to higher silhouette coefficients.

k-means PCA+k-means LE+k-means
cluster sil # genes sil # genes sil # genes
1 0.0200 65 0.7329 126 0.6535 103
2 0.3067 146 0.6221 60 0.7049 125
3 0.4078 180 0.7002 168 0.6862 174
4 0.4068 234 0.6840 198 0.6848 154
5 0.3401 255 0.7423 157 0.7831 97
6 0.2960 252 0.7033 130 0.7949 389
7 0.3442 90 0.6795 126 0.7369 120
8 0.6509 9 0.6800 65 0.6953 270
9 0.3900 254 0.6393 190 0.7800 91
10 0.2162 34 0.7130 187 0.7046 79
11 0.3056 112 0.6517 182 0.7606 141
12 0.3531 165 0.7162 155 0.7487 122
13 0.4636 182 0.6925 117 0.9889 3
14 0.4267 167 0.7422 205 0.7118 125
15 0.6529 114 0.6968 184 0.5997 85
16 0.1593 86 0.5266 9 0.7214 236
17 0.5488 13 0.6792 84 0.6839 83
18 0.4323 253 0.6956 211 0.7380 135
19 0.1749 20 0.7151 118 0.6466 72
20 0.3076 133 0.6926 170 0.7243 121
21 0.4314 174 0.7041 115 0.7461 199
22 0.4394 130 0.7342 116 0.7442 275
23 0.4538 210 0.7252 192 0.6849 115
24 0.4366 138 0.6792 151 0.8534 102