Table 3.

Comparison between supervised and unsupervised methods: GO categories related to the optic fissure closure that are associated to clusters derived from unsupervised (no data labels) and supervised (labeled data) methods. Using labels that are computed directly from the measured data appears to provide more biological meaningful associations than unsupervised methods.

Unsupervised methods	Schroedinger Eigenmaps + WGCNA / D-labels
eye morphogenesis
eye development
eye photoreceptor cell development
eye photoreceptor cell differentiation
photoreceptor cell development
embryonic morphogenesis
morphogenesis of a branching structure
sensory organ development
	camera type eye morphogenesis
	retina morphogenesis in camera type eye
	retinal bipolar neuron differentiation