Figure 2.

Effect of EL, NAC, or L-NAC pretreatment on viability of PQ-challenged cells. The viability of cells pretreated with control media (no pretreatment), or 5.0 mM NAC- (NAC Pretreatment), L-NAC- (L-NAC pretreatment) or empty liposome-containing media (EL pretreatment) for 4 h prior to 24 h PQ challenge (0, 0.1, 0.5, or 1.0 mM) was assessed using the MTT assay. Bars represent mean ± S.E.M. of 3 independent experiments performed in octuplet. *denotes significant difference relative to cells with no pretreatment (P < .05); N.D.: not determined.