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. 2011 Feb 16;155(4):2036–2048. doi: 10.1104/pp.110.171330

Table III. In vitro virus neutralization activity of seed-produced HA78 scFv-Fcs.

In vitro virus neutralization efficiencies of the plant-produced HA78 scFv-Fcs as well as of a CHO-produced HA78 mAb are all in the same range and thereby similar to previously reported seed-produced HA78 mAbs and a scFv-Fc (Van Droogenbroeck et al., 2007; Loos et al., 2011). As a negative control, a recombinant human antibody against Hantavirus was used.

Sample IC50
HA78 IgG CHO 15.51
HA78 IgG plant 13.70
wt-PhHA78scSEC 15.95
TKO-PhHA78scSEC 17.22
wt-PhHA78scKDEL 14.51
Negative control >50