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In contrast to CHO- and seed-produced 2G12 IgG (Loos et al., 2011), the seed-produced scFv-Fc does not show in vitro neutralization activity.
| Sample | IC50 |
| 2G12 IgG CHO | 3.15 |
| 2G12 IgG plant | 0.26 |
| wt-Ph2G12scSEC | >20 |
| Negative control | >50 |
