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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Mol Microbiol. 2010 Sep 29;78(3):770–787. doi: 10.1111/j.1365-2958.2010.07366.x

Fig. 2. Ranked plots showing phenotype distributions for CQ with and without VP.

Fig. 2

A. Ranked distribution for VP response against CQ response in the cross. VP response is continuously distributed and inversely related to CQ response. Progeny that had high VP IC50 values had lower CQ IC50 values. This negative relationship was consistent with all other reversal agents tested.

B. Ranked distribution for CQ response against fold change in the presence of VP. Fold change partitions the drug responses into two groups (CQS and CQ resistant) depending on the HB3 and Dd2 pfcrt allele.