TABLE 1.

Voltage dependence of activation of BgNa_v splices variants before and after application of 300 nm Lqh-dprIT₃

Each value represents the mean ± S.D. for at least five oocytes.

	Toxin-free		Lqh-dprIT3 (300 nm)
	V0.5	k	V0.5	k1	A1	V0.5	k2	A2
					%			%
BgNav1-1	−23.2 ± 1.0	6.3 ± 0.3	−21.0 ± 0.4	5.3 ± 0.3	20 ± 5a	−62.8 ± 2.6	7.9 ± 0.5	80 ± 5a
BgNav1-1a	−28.4 ± 2.1	4.1 ± 0.6	−28.1 ± 1.5	5.0 ± 0.3	82 ± 5	−60.0 ± 3.3	10.4 ± 1.6	18 ± 5
BgNav1-2	−25.2 ± 2.8	5.1 ± 1.1	−25.5 ± 2.1	6.1 ± 1.4	81 ± 3	−58.1 ± 1.2	8.6 ± 0.8	19 ± 3
BgNav1-3	−30.4 ± 2.1	4.3 ± 0.6	−30.6 ± 1.5	5.5 ± 0.4	86 ± 4	−68.7 ± 0.8	5.4 ± 0.3	14 ± 4
BgNav5	−35.9 ± 2.6	3.7 ± 0.5	−35.7 ± 0.7	4.0 ± 0.4	77 ± 1	−59.3 ± 3.0	11.5 ± 0.9	23 ± 1
BgNav6	−27.9 ± 2.4	4.1 ± 0.9	−29.2 ± 2.6	5.2 ± 0.9	79 ± 5	−59.0 ± 5.8	10.9 ± 2.3	21 ± 3
BgNav7	−31.7 ± 1.9	4.8 ± 0.4	−32.5 ± 2.3	3.1 ± 0.6	79 ± 6	−56.7 ± 2.8	11.8 ± 2.1	21 ± 5
BgNav8	−26.5 ± 1.0	4.8 ± 0.2	−26.2 ± 0.9	5.5 ± 0.2	86 ± 3	−60.0 ± 0.5	8.2 ± 0.2	14 ± 3
BgNav9	−30.7 ± 3.1	6.4 ± 1.2	−31.0 ± 2.9	7.5 ± 1.4	82 ± 5	−60.0 ± 2.6	10.1 ± 1.5	18 ± 5
BgNav10	−34.1 ± 2.4	3.5 ± 0.5	−35.8 ± 0.7	3.9 ± 0.7	75 ± 6	−58.6 ± 2.0	14.3 ± 2.6	25 ± 6
BgNav11	−49.3 ± 2.0	−3.2 ± 0.5	−43.2 ± 2.7	5.6 ± 0.7	73 ± 3	−73.7 ± 3.0	2.9 ± 1.1	27 ± 3

^a Significant differences from other splice variants (p < 0.05).