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. 2011 Feb 28;286(18):15875–15882. doi: 10.1074/jbc.M111.227819

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 1. — KO mice (Ca_vβ2^−/flox/MerCreMer^tg/0 mice after induction for cacnb2 gene deletion by Tamoxifen), like controls receiving identical Tamoxifen treatment, did not exhibit any signs of cardiac decompensation. A–I, heart rate (A), heart weight (B and C), lung weight (D and E), liver weight (G and H), and lung (F) and liver water content (I) (given as the percentage of organ wet weight) were not significantly different among the three genotypes. Control 1, Ca_Vβ2^+/flox/MerCreMer^tg/0; control 2, Ca_Vβ2^−/flox. Values are shown as mean ± S.E.