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. 2011 Mar 2;286(18):16131–16139. doi: 10.1074/jbc.M110.209254

FIGURE 5.

FIGURE 5.

Effect of the E33A-L1 mutation on the cutoff for 1-alcohol inhibition of L1 adhesion. Values shown are the mean ± S.E. levels of L1 adhesion (top panels) and percent inhibition of L1 adhesion (bottom panels) for cells expressing WT-L1 (left panels, n = 4) and E33A-L1 (right panels, n = 6). The abscissa labels show the identity and concentration of each 1-alcohol as follows: (number of carbons)/(concentration, mm); e.g. C10/5 represents 5 mm 1-decanol. In WT-L1-expressing cells, the cutoff is between 1-butanol and 1-pentanol; in E33A-L1-expressing cells, the cutoff is between 1-decanol and 1-undecanol. Ethanol inhibition of L1 adhesion is antagonized by 1-pentanol in WT-L1- and by 1-undecanol in E33A-L1-expressing cells. *, p < 0.01; **, p < 0.001.