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. 2011 Mar 23;286(18):16229–16237. doi: 10.1074/jbc.M110.204701

FIGURE 1.

FIGURE 1.

Effect of different doses of PEG-8 on CNV size and time course of PEG-induced CNV. A and B, no CNV was found in the naive and PBS-injected animals, respectively. C–G, shown is CNV (green) after subretinal injections of different doses of PEG-8. F and H, a PEG-8 dose of 1.0 mg induced CNV of maximal size. I, after a subretinal injection of 1 mg of PEG-8, CNV was detected for the first time at day 3 post-injection, was fully developed at day 5, and then started to reduce in size from days 21 to 42. *, p < 0.05 versus a dose of 0.125 mg (H) or day 3 post-injection (I). Scale bar = 100 μm.