FIGURE 5.
Effect of PEG-8 on complement activity in serum and RPE-choroid. A subretinal injection of PEG-8 did not affect total (A) and alternative (B) complement activities in mouse serum at any day post-treatment. Western blot analysis of RPE-choroid tissue showed that PEG-8 increased C3 split products (43 and 23 kDa) at day 1 post-injection (C–E) and C9 at all days post-injection (C and F). b-actin, β-actin. *, p < 0.05.