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. 2011 Mar 16;286(18):16392–16401. doi: 10.1074/jbc.M110.150177

TABLE 2.

Michaelis constants for GSH or LTA₄-Me

Values are the mean ± S.D.

	Wild type			R31A			R104A
	pH 7.0	pH 8.0	pH 9.0	pH 7.0	pH 8.0	pH 9.0	pH 7.0	pH 8.0	pH 9.0
K_m^GSH mm	0.520 ± 0.032	0.188 ± 0.027^a	0.189 ± 0.017^a	0.104 ± 0.004	0.0541 ± 0.0053^a	0.0669 ± 0.0078^a	16.7 ± 0.3	12.8 ± 1.6^c	24.6 ± 1.2^a
K_m^LTA4-Me μm	4.08 ± 0.90	3.44 ± 0.43	4.45 ± 0.65	6.09 ± 1.62	5.55 ± 0.62	8.39 ± 1.84	3.85 ± 0.38	7.09 ± 1.18^c	5.69 ± 0.05^b

^a p < 0.001 as compared to pH 7.0.

^b p < 0.05 as compared to pH 7.0.

^c p < 0.01 as compared to pH 7.0.