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. 2011 Mar 18;286(18):16504–16515. doi: 10.1074/jbc.M110.208447

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© 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 5. — Effects of MB on rotenone-induced neurological and behavioral deficit in rats. A, MB prevents rat body weight loss induced by rotenone treatment. B, MB improved coordinated motor function deficiency induced by chronic rotenone treatment. **, significant difference between the indicated groups (p < 0.01). An asterisk in the individual sessions indicates that there is significant difference between ROT/Sal and both of the other two groups (p < 0.05). C, effects of MB on randomized blinded neurological assessments. ***, significant difference between the indicated groups (p < 0.001). D and E, effects of MB on catalepsy measurements in rotenone- and MB-treated rats with the bar test (D) and grid test (E). F, effects of MB on stride length in rotenone- and MB-treated rats in the gait test. ROT, rotenone-treated; Sal, saline (vehicle for MB); Veh, vehicle for rotenone. * and **, significant difference between the indicated groups in D–F. Error bars, S.E.