Effects of MB and rotenone on dopamine and DOPAC levels, mitochondrial complex I-III activity, and total ROS in vivo. A and B, effects of rotenone and MB treatment on striatum dopamine (A) and DOPAC (B) levels. C and D, mitochondrial I-III activity (C) and total ROS (D) in rotenone- and MB-treated rats. All numbers were normalized to percentage of control groups. * and **, significant difference between the indicated groups in all panels. Error bars, S.E.