Figure 1. (P)RR immunoreactivity in kidneys from sham-operated and Ang II-infused rat.
A. paraffin-embedded kidney sections (3 μ) showing (P)RR specific staining (brown; arrow heads) on the apical membrane of the collecting duct cells co-localizing with basolateral AE1 immunoreactivity (Bajoran purple; asterisk) in type-A intercalated cells. (original magnification, × 1000). B. Densitometric analysis of the (P)RR intensity of sham-operated (B and D) and Ang II-infused rats (C and E) showing reduced number of positive cells in renal medullary tissues of Ang II-infused compared to sham-operated rats (F) but not in the renal cortex (G). Scale bar: 100 μm. Values are mean ± S.E. *P<0.05 vs. sham-operated rats.