Table 3.
Prednisone Doses and Serum Bilirubin Concentrations at 1 Yr and Causes of Eventual Death in 19 Patients Who Died More Than 1 Yr After Liver Transplantation
| OT No. |
Days survival |
Age at operation (yr) |
Original disease | Pathology of graft | Main cause of death | Bilirubin at 1 yr (mg%) |
Prednisone dose at 1 yr (mg/kg/day) |
|---|---|---|---|---|---|---|---|
| 8 | 400 | 1.5 | Hepatoma | Biliary obstruction; metastatic tumor |
Recurrent cancer | 12.5 | 0.33 |
| 13 | 901 (881 + 20)a |
2 | Biliary atresia | 1. Chronic rejection 2. Aspergillus infection |
Infection after retransplantation | 16.4 | 0.39 |
| 14 | 436 (379 + 57) |
16 | Hepatoma | 1. Chronic rejection 2. Normal |
Technical and infectious compli- cations after second grafting |
37.5 | 0.26 |
| 16 | 404 (65 + 339)a |
2 | Biliary atresia | 1. Chronic rejection 2. Chronic rejection |
Liver failure | 10.0 | 1.25 |
| 19 | 1238 | 4 | Biliary atresia | Chronic rejection | Liver failure; lung infection | 0.7 | 1.5 |
| 27 | 2190 | 11 | Wilson’s disease | Partial biliary obstruction; chronic rejection |
Liver failure | 0.5 | 0.33 |
| 29 | 377 | 5 | Biliary atresia | Chronic hepatitis | Liver failure | 7.0 | 0.6 |
| 36 | 623 | 28 | Chronic aggressive hepatitis | Chronic aggressive hepatitis | Liver failure; nocardial infection | 1.0 | 0.38 |
| 54 | 586 (566 + 22)a |
22 | Chronic aggressive hepatitis | 1. Biliary obstruction 2. Normal |
Hemorrhagic pancreatitis; infection after retransplantation |
0.6 | 0.5 |
| 55 | 780 | 6 | Chronic aggressive hepatitis | Biliary obstruction | Liver failure | 28.0 | 0.7 |
| 58 | 407 | 34 | Chronic aggressive hepatitis | Biliary obstruction | Liver failure | 40.8 | 0.36 |
| 74 | 855 (820 + 35)a |
16 | Alpha1-antitrypsin deficiency | 1. Chronic rejection 2. Normal |
Injection after retransplantation | 0.8 | 0.7 |
| 78 | 747 | 48 | Duct cell carcinoma | Tumor recurrence | Recurrent cancer | 0.5 | 0.29 |
| 89 | 590 | 3.5 | Biliary atresia | Chronic rejection; thrombosis of intrahepatic portal branches |
Infection | 0.4 | 0.71 |
| 98 | 511 (37 + 474)a |
1 | Biliary atresia | 1. Acute rejection 2. Chronic rejection |
Liver failure | 2.3 | 2.5 |
| 103 | 1085 (682 + 403)a |
21 | Primary biliary cirrhosis | 1. Chronic rejection 2. Chronic rejection; massive liver necrosis |
Infection after conversion of cholecystojejunostomy to choledochojejunostomy; liver failure |
4.0 | 0.55 |
| 106 | 469 | 19 | Chronic aggressive hepatitis | Healed acute rejection | Infection; liver failure | 2.0 | 0.33 |
| 113 | 695 | 3 | Biliary atresia | Massive liver necrosis | Systemic chicken pox; bacterial infection |
0.6 | 1.7 |
| 126 | 497 | 11 | Biliary atresia | Chronic rejection; portal vein thrombosis |
Liver failure; gastrointestinal hemorrhage |
4.0 | 0.8 |
Underwent retransplantation. Figures in parentheses are survival of first and second grafts.