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. Author manuscript; available in PMC: 2011 May 10.
Published in final edited form as: Gastroenterology. 1979 Aug;77(2):375–388.

Table 3.

Prednisone Doses and Serum Bilirubin Concentrations at 1 Yr and Causes of Eventual Death in 19 Patients Who Died More Than 1 Yr After Liver Transplantation

OT
No.
Days
survival
Age at
operation
(yr)
Original disease Pathology of graft Main cause of death Bilirubin
at 1 yr
(mg%)
Prednisone
dose at 1 yr
(mg/kg/day)
8 400 1.5 Hepatoma Biliary obstruction;
metastatic tumor
Recurrent cancer 12.5 0.33
13 901
(881 + 20)a
2 Biliary atresia 1. Chronic rejection
2. Aspergillus infection
Infection after retransplantation 16.4 0.39
14 436
(379 + 57)
16 Hepatoma 1. Chronic rejection
2. Normal
Technical and infectious compli-
cations after second grafting
37.5 0.26
16 404
(65 + 339)a
2 Biliary atresia 1. Chronic rejection
2. Chronic rejection
Liver failure 10.0 1.25
19 1238 4 Biliary atresia Chronic rejection Liver failure; lung infection 0.7 1.5
27 2190 11 Wilson’s disease Partial biliary obstruction;
chronic rejection
Liver failure 0.5 0.33
29 377 5 Biliary atresia Chronic hepatitis Liver failure 7.0 0.6
36 623 28 Chronic aggressive hepatitis Chronic aggressive hepatitis Liver failure; nocardial infection 1.0 0.38
54 586
(566 + 22)a
22 Chronic aggressive hepatitis 1. Biliary obstruction
2. Normal
Hemorrhagic pancreatitis; infection
after retransplantation
0.6 0.5
55 780 6 Chronic aggressive hepatitis Biliary obstruction Liver failure 28.0 0.7
58 407 34 Chronic aggressive hepatitis Biliary obstruction Liver failure 40.8 0.36
74 855
(820 + 35)a
16 Alpha1-antitrypsin deficiency 1. Chronic rejection
2. Normal
Injection after retransplantation 0.8 0.7
78 747 48 Duct cell carcinoma Tumor recurrence Recurrent cancer 0.5 0.29
89 590 3.5 Biliary atresia Chronic rejection; thrombosis of
intrahepatic portal branches
Infection 0.4 0.71
98 511
(37 + 474)a
1 Biliary atresia 1. Acute rejection
2. Chronic rejection
Liver failure 2.3 2.5
103 1085
(682 + 403)a
21 Primary biliary cirrhosis 1. Chronic rejection
2. Chronic rejection; massive liver
necrosis
Infection after conversion of
cholecystojejunostomy to
choledochojejunostomy; liver failure
4.0 0.55
106 469 19 Chronic aggressive hepatitis Healed acute rejection Infection; liver failure 2.0 0.33
113 695 3 Biliary atresia Massive liver necrosis Systemic chicken pox; bacterial
infection
0.6 1.7
126 497 11 Biliary atresia Chronic rejection; portal vein
thrombosis
Liver failure; gastrointestinal
hemorrhage
4.0 0.8
a

Underwent retransplantation. Figures in parentheses are survival of first and second grafts.